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Lewin’s Essential Genes
Authors: Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. KilpatrickOVERVIEW
Lewin’s Essential GENES, Fourth Edition provides a clear and concise overview, as well as up-to-date concepts and techniques in the area of molecular genetics. This text focuses on essential topics, background, and introductory material on the structure and function of genes and genomes and their associated cellular processes.
The Fourth Edition is organised into four parts. Part I: Genes and Chromosomes, Part II: DNA Replication and Recombination, Part III: Gene Expression, and Part IV: Gene Regulation. The content of the text has been added and updated to reflect the research advances in many fields, particularly in Chromatin, Eukaryotic Transcription Regulation, and Epigenetics.
Each new print copy includes a Navigate 2 Companion Website that features interactive and informative learning resources that gauge understanding and help students study more effectively.
Features and Benefits
- CRISPR/Cas9 genome editing is discussed in multiple chapters from different perspectives
- A general reorganisation for a more logical flow of topics
- Unique pedagogical features that help students with historical context, give opportunities for practice and assessment, and use critical thinking skills to fully understand the material
TABLE OF CONTENTS
- Chapter 1 Genes Are DNA and Encode RNAs and Polypeptides
- Chapter 2 Methods in Molecular Biology and Genetic Engineering
- Chapter 3 The Interrupted Gene
- Chapter 4 The Content of the Genome
- Chapter 5 Genome Sequences and Evolution
- Chapter 6 Clusters and Repeats
- Chapter 7 Chromosomes
- Chapter 8 Chromatin
- Chapter 9 Replication Is Connected to the Cell Cycle
- Chapter 10 The Replicon: Initiation of Replication
- Chapter 11 DNA Replication
- Chapter 12 Extrachromosomal Replicons
- Chapter 13 Homologous and Site-Specific Recombination
- Chapter 14 Repair Systems
- Chapter 15 Transposable Elements and Retroviruses
- Chapter 16 Prokaryotic Transcription
- Chapter 17 Eukaryotic Transcription
- Chapter 18 RNA Splicing and Processing
- Chapter 19 mRNA Stability and Localization
- Chapter 20 Catalytic RNA
- Chapter 21 Translation
- Chapter 22 Using the Genetic Code
- Chapter 23 The Operon
- Chapter 24 Phage Strategies
- Chapter 25 Eukaryotic Transcription Regulation
- Chapter 26 Epigenetics
- Chapter 27 Noncoding RNA
- Chapter 28 Regulatory RNA
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